General Pathology

Introduction

Diseases of the Immune system

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Cell Injury & Adaptation

  • Reversible & irreversible injury
  • Necrosis
  • Apoptosis
  • Cellular adaptations
    • Atrophy
    • Hypertrophy
    • Hyperplasia
    • Metaplasia

Inflammation

  • Acute inflammation
  • Chronic inflammation
  • Granulomatous inflammation

Healing & Repair

  • Tissue repair
  • Wound healing
  • Factors affecting healing

Hemodynamic Disorders

  • Edema
  • Thrombosis
  • Embolism
  • Infarction
  • Shock

Genetic Disorders

  • Mendelian disorders
  • Chromosomal disorders
  • Mitochondrial disorders

Immunity & Hypersensitivity

  • Innate & adaptive immunity
  • Hypersensitivity reactions
    • Type I (Anaphylaxis)
    • Type II (Cytotoxic)
    • Type III (Immune complex)
    • Type IV (Delayed-type)
  • Autoimmune diseases
  • Transplant rejection
  • Immunodeficiency Syndromes
  • AIDS

Infectious Diseases

  • Host-parasite interaction
  • Common bacterial infections
  • Common viral infections
  • Common fungal infections

Neoplasia

  • Definition of tumors
  • Benign vs. malignant tumors
  • Tumor nomenclature
  • Tumor biology
  • Carcinogenesis
  • Tumor markers

Environmental Pathology

  • Radiation injury
  • Chemical injury
  • Occupational diseases

Nutritional Disorders

  • Vitamin deficiencies
  • Obesity
  • Starvation

Amyloidosis

  • Types
  • Pathogenesis
  • Diagnosis

Cellular Aging

  • Mechanisms of aging
  • Telomeres & free radical theory

Basic Diagnostic Techniques in Pathology

  • Histopathology
  • Cytology
  • Immunohistochemistry
  • Molecular techniques
    • PCR
    • FISH
    • Flow cytometry